Peptide Database

Peptide NameCupiennin-2c

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC172H296N44O44S

DescriptionStandard

        AFGTILKALAKIAGKVVKKLATKPGATYMLKENLQ
    

Molecular Weight3716.52 Da

Isoelectric Point (pI)10.22

Net Charge (pH 7.0)5.79

Net Charge (pH 7.4) 5.59

Charge Density (pH 7.0) 0.1654

GRAVY Index0.23

Hydrophobic Moment 0.70

Boman Index0.13

Instability Index14.70

Aliphatic Index 111.71

Aromaticity 0.0571

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1430.47

LogP -9.97

H-bond Donors 49.0

H-bond Acceptors 51.0

Rotatable Bonds 130.0

Heavy Atoms 261.0

Ring Count 3.0

Amide Bonds 36.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0050918 VERIFIED: NO

Provenance & Taxonomy

OrganismCupiennius salei [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0311494 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic