MYP_053828
Basic Information
NOSO-95179 46
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
not Standard
9 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KXAGXPHKX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0130187 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Dab(?OH) = ((2S,3S)-2,4-diamino 3-hydroxy butyric acid at 2; D-Orn = D-ornithine at 5; Dha = Z-?,??dehydroarginine at 9; Dab(?OH) = ((2S,3S)-2,4-diamino 3-hydroxy butyric acid; D-Orn = D-ornithine; Dha = Z-?,??dehydroarginine; Dbt = ?,??diamino butane
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
E. cloacae ATCC BAA-2468
4 μg/mL
MIC
RECORD: Rec_0146050 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Dab(?OH) = ((2S,3S)-2,4-diamino 3-hydroxy butyric acid at 2; D-Orn = D-ornithine at 5; Dha = Z-?,??dehydroarginine at 9; Dab(?OH) = ((2S,3S)-2,4-diamino 3-hydroxy butyric acid; D-Orn = D-ornithine; Dha = Z-?,??dehydroarginine; Dbt = ?,??diamino butane
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Klebsiella pneumoniae ATCC 43816
4 μg/mL
MIC
RECORD: Rec_0221389 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Dab(?OH) = ((2S,3S)-2,4-diamino 3-hydroxy butyric acid at 2; D-Orn = D-ornithine at 5; Dha = Z-?,??dehydroarginine at 9; Dab(?OH) = ((2S,3S)-2,4-diamino 3-hydroxy butyric acid; D-Orn = D-ornithine; Dha = Z-?,??dehydroarginine; Dbt = ?,??diamino butane
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli ATCC 25922
4 μg/mL
MIC
RECORD: Rec_0264765 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Dab(?OH) = ((2S,3S)-2,4-diamino 3-hydroxy butyric acid at 2; D-Orn = D-ornithine at 5; Dha = Z-?,??dehydroarginine at 9; Dab(?OH) = ((2S,3S)-2,4-diamino 3-hydroxy butyric acid; D-Orn = D-ornithine; Dha = Z-?,??dehydroarginine; Dbt = ?,??diamino butane
Bio-Activity Profile
Hemolytic
mouse RBCs
100 μM
Hemolysis