Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC773H1209N225O233S4

DescriptionStandard

        MAKFKLNEQRRAFLDAIAYCEGTDNGRQQTRNHGYDVVVGGSLFSDYSKHPDRLVRLRPGLSSTAAGRYQLLSRYYDVYKKQLGLPDFGPDSQDQIALQQISERKALEDIDAGRIESAVAKCNKTWASLPGSPYGQHTYSMAVFLEQFRKAGGKVAA
    

Molecular Weight17510.50 Da

Isoelectric Point (pI)9.23

Net Charge (pH 7.0)4.75

Net Charge (pH 7.4) 4.31

Charge Density (pH 7.0) 0.0303

GRAVY Index-0.58

Hydrophobic Moment 0.76

Boman Index-0.10

Instability Index39.60

Aliphatic Index 72.17

Aromaticity 0.1019

Extinction Coeff. Reduced 18910.00

Extinction Coeff. Oxidized 19035.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7461.44

LogP -80.58

H-bond Donors 262.0

H-bond Acceptors 245.0

Rotatable Bonds 585.0

Heavy Atoms 1235.0

Ring Count 26.0

Amide Bonds 171.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0310678 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage Sortsne [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic