Peptide Database

Peptide NameCyclotide Viphi H

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC135H205N33O40S6

DescriptionStandard

        CAESCVWIPCTVTAIVGCSCSWGVCYNGIP
    

Molecular Weight3122.66 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.30

Net Charge (pH 7.4) -1.59

Charge Density (pH 7.0) -0.0432

GRAVY Index1.02

Hydrophobic Moment 0.25

Boman Index0.43

Instability Index21.95

Aliphatic Index 84.33

Aromaticity 0.1000

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1122.99

LogP -11.38

H-bond Donors 45.0

H-bond Acceptors 45.0

Rotatable Bonds 89.0

Heavy Atoms 214.0

Ring Count 7.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0052119 VERIFIED: NO

Provenance & Taxonomy

OrganismViola philippica [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytotoxic

TargetCancer cell line

RECORD: Rec_0326022 VERIFIED: YES