Peptide Database

Peptide NameHuwentoxin-III

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC169H253N45O45S7

DescriptionStandard

        DCAGYMRECKEKLCCSGYVCSSRWKWCVLPAPW
    

Molecular Weight3859.55 Da

Isoelectric Point (pI)8.32

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0516

GRAVY Index-0.19

Hydrophobic Moment 0.37

Boman Index-0.01

Instability Index69.71

Aliphatic Index 47.27

Aromaticity 0.1515

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1439.22

LogP -10.87

H-bond Donors 58.0

H-bond Acceptors 54.0

Rotatable Bonds 119.0

Heavy Atoms 266.0

Ring Count 10.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0315697 VERIFIED: YES

Provenance & Taxonomy

OrganismSelenocosmia huwena [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-14; 9-20; 15-27

Bio-Activity Profile

Function

Toxin

Targetcockroach

Activity192000000 μM

MethodED50