Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length506 amino acids

Chemical FormulaC2527H4017N697O700S19

DescriptionStandard

        MSSAPAFRCQHRPRGVAWLCLLLLLPVCVPATVTNPGIKAWLTRSSLEFGRRFGLELFQSTLQKEHELNLTGSYNIPLLGNLTYAVPRIHIHELQMNDSTLDFAEDVGVRLMVQRAQIQLSADWAAQLGAIQDSGSVELRMQDLAVAAVLGVSEDGGGRPTVWSAGCDTHGTDLHMEFHRGYSWIYNLLAPLLQRTLRQQLNKQLCLELQRGIDKLDAALKHMKVSTQLDAFAAIDYSLLGPPAFTAEHGDIVLKGEIFRVGMYQQRRSALPVALPMSLPVALPLALPTLTPKALPVAREPMLLMAVTEFVANSAAFTYFTAGALRRNISSDMLPQRFPFQLRTKSMGVFSPQLQEHYGDQPMELHLWARRQPLLSCHPDALHGTLFSSAEAFVVLPNTTRVPVFLLNIDANVTGKPTITRNRLGGTVRLTGLSVTQVASNVGPVEVKRLETLLKFGLWLFGVPRANKWLQAGIPLPLPHGLSLLRPRVSLQEDFVLIATDLQYEP
    

Molecular Weight55971.41 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)5.72

Net Charge (pH 7.4) 4.63

Charge Density (pH 7.0) 0.0113

GRAVY Index0.07

Hydrophobic Moment 0.74

Boman Index0.11

Instability Index50.71

Aliphatic Index 103.52

Aromaticity 0.0751

Extinction Coeff. Reduced 57410.00

Extinction Coeff. Oxidized 57785.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0337424 VERIFIED: NO

Provenance & Taxonomy

OrganismPipra filicauda [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria