Peptide Database

Peptide NameAlpha-like toxin Lqh3 (Lqh III), (LqhIII)

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC301H459N87O94S8

DescriptionStandard

        VRDGYIAQPENCVYHCFPGSSGCDTLCKEKGGTSGHCGFKVGHGLACWCNALPDNVGIIVEGEKCHS
    

Molecular Weight7056.91 Da

Isoelectric Point (pI)6.02

Net Charge (pH 7.0)-1.99

Net Charge (pH 7.4) -2.54

Charge Density (pH 7.0) -0.0297

GRAVY Index-0.18

Hydrophobic Moment 0.41

Boman Index0.10

Instability Index24.36

Aliphatic Index 61.04

Aromaticity 0.0746

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2849.34

LogP -33.83

H-bond Donors 104.0

H-bond Acceptors 104.0

Rotatable Bonds 226.0

Heavy Atoms 490.0

Ring Count 13.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0035713 VERIFIED: NO

Provenance & Taxonomy

OrganismLeiurus hebraeus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0109195 VERIFIED: YES

Provenance & Taxonomy

OrganismLeiurus quinquestriatus hebraeus [Animal]

FamilySodium channel inhibitor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide12-65; 16-37; 23-47; 27-49

Bio-Activity Profile

Function

Toxin Venom Sodium channel inhibitor family Ion channel inhibitor Host defense