Peptide Database

Peptide NamePln149 (Plantaricin 149; Bacteriocin; Derivatives: Pln149a)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC111H190N30O28S

DescriptionStandard

        YSLQMGATAIKQVKKLFKKKGG
    

Molecular Weight2424.95 Da

Isoelectric Point (pI)10.40

Net Charge (pH 7.0)5.75

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.2615

GRAVY Index-0.45

Hydrophobic Moment 0.80

Boman Index-0.07

Instability Index13.71

Aliphatic Index 75.45

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 977.41

LogP -8.07

H-bond Donors 34.0

H-bond Acceptors 35.0

Rotatable Bonds 89.0

Heavy Atoms 170.0

Ring Count 2.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0350226 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct based on Lactiplantibacillus plantarum [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermLipidation

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetStaphylococcus aureus

Activity1.0 μM

MethodMIC

RECORD: Rec_0400450 VERIFIED: NO

Provenance & Taxonomy

OrganismLactiplantibacillus plantarum [Bacterium]; Bacteria [Bacterium]

Tax ID1590; 2