Peptide Database

Peptide NameSLAY-screened peptide P4958

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC34H53N7O10S

DescriptionStandard

        PYCLAVS
    

Molecular Weight751.89 Da

Isoelectric Point (pI)5.91

Net Charge (pH 7.0)-0.05

Net Charge (pH 7.4) -0.13

Charge Density (pH 7.0) -0.0075

GRAVY Index1.23

Hydrophobic Moment 0.07

Boman Index0.46

Instability Index36.09

Aliphatic Index 111.43

Aromaticity 0.1429

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 264.39

LogP -1.68

H-bond Donors 11.0

H-bond Acceptors 11.0

Rotatable Bonds 20.0

Heavy Atoms 52.0

Ring Count 2.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0087344 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/