Peptide Database

Peptide NameDermaseptin-S13 (DRS-S13)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC355H580N98O118S5

DescriptionStandard

        MAFLKKSLFLVLFLGLVSLSICDEEKRENEDEENQEDDEQSEMRRGLRSKIKEAAKTAGKMALGFVNDMAGEQ
    

Molecular Weight8269.31 Da

Isoelectric Point (pI)4.69

Net Charge (pH 7.0)-5.48

Net Charge (pH 7.4) -5.74

Charge Density (pH 7.0) -0.0751

GRAVY Index-0.56

Hydrophobic Moment 0.64

Boman Index-0.13

Instability Index64.88

Aliphatic Index 78.90

Aromaticity 0.0548

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3564.98

LogP -35.42

H-bond Donors 122.0

H-bond Acceptors 118.0

Rotatable Bonds 299.0

Heavy Atoms 576.0

Ring Count 4.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0267615 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa sauvagei [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetGram-negative and Gram-positive bacteria