Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length48 amino acids

Chemical FormulaC223H357N57O75S5

DescriptionStandard

        MKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCPNSVFVCC
    

Molecular Weight5196.88 Da

Isoelectric Point (pI)4.55

Net Charge (pH 7.0)-3.52

Net Charge (pH 7.4) -3.79

Charge Density (pH 7.0) -0.0733

GRAVY Index-0.15

Hydrophobic Moment 0.54

Boman Index0.06

Instability Index36.25

Aliphatic Index 71.04

Aromaticity 0.0625

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2137.40

LogP -23.23

H-bond Donors 75.0

H-bond Acceptors 77.0

Rotatable Bonds 177.0

Heavy Atoms 360.0

Ring Count 5.0

Amide Bonds 50.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0361103 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus pyogenes [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

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