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MYP_053729
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Basic Information
Lantibiotic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
48 amino acids
C223H357N57O75S5
Standard
Sequence
MKNSKDILTNAIEEVSEKELMEVAGGKKGSGWFATITDDCPNSVFVCC
Physicochemical Analysis
5196.88 Da
4.55
-3.52
-3.79
-0.0733
-0.15
0.54
0.06
36.25
71.04
0.0625
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2137.40
-23.23
75.0
77.0
177.0
360.0
5.0
50.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0156811 VERIFIED: YES
Provenance & Taxonomy
Streptococcus pyogenes serotype M3 [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic
Gram-positive bacteria
PMID12122206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12122206/
RECORD: Rec_0168049 VERIFIED: NO
Provenance & Taxonomy
Streptococcus dysgalactiae subsp. equisimilis [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal
Gram-positive bacteria
Qualitative functional evidence
PMID16461700 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16461700/; https://www.uniprot.org/uniprotkb/Q38L33/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0198491 VERIFIED: YES
Provenance & Taxonomy
Streptococcus pyogenes serotype M49 [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic
Gram-positive bacteria
PMID18820018 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18820018/
RECORD: Rec_0310240 VERIFIED: NO
Provenance & Taxonomy
Streptococcus pyogenes GA06023 [Bacterium]
Lantibiotic
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal
Gram-positive bacteria
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/U2WEH8/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0351785 VERIFIED: NO
Provenance & Taxonomy
Streptococcus pyogenes [Bacterium]
Lantibiotic
Structure & Mods
linear lantibiotic precursor [Linear]
post-translationally modified ribosomal peptide [Modified]
Lantibiotic-family precursor annotation suggests post-translational lanthionine/methyllanthionine thioether crosslinks in the mature peptide
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic
Gram-positive bacteria
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A4V6IY23/entry
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