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MYP_053713
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Basic Information
C18-p1b
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-H1N1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Binding inhibition
Standard
15 amino acids
C88H131N27O20
Standard
Sequence
DFRRLPGAFWQLRQP
Physicochemical Analysis
1887.15 Da
11.70
1.76
1.56
0.1174
-0.90
0.64
-0.24
88.19
58.67
0.2000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
778.11
-5.05
27.0
22.0
57.0
135.0
6.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0337302 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 40.0%, C 60.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0355111 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Alkylated(C18)
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
H1N1(A/PR/8/34):inhibition of virus infection in Madin-Darby canine kidney(MDCK) cells
52 μM
IC50
PaperPubMed PMID: 19558186 PMID19558186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19558186/
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