Peptide Database

Peptide NameDEFSN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length92 amino acids

Chemical FormulaC439H714N132O141S7

DescriptionStandard

        MKTLVLLSALVLLAFQVQADPIQNTDEETNTEEQPGEEDQAVSISFGGQEGSDLHEKSLRGLLCYCREGRCKRGERVRGTCGIRFLYCCPRR
    

Molecular Weight10321.62 Da

Isoelectric Point (pI)5.39

Net Charge (pH 7.0)-2.44

Net Charge (pH 7.4) -2.83

Charge Density (pH 7.0) -0.0266

GRAVY Index-0.46

Hydrophobic Moment 0.68

Boman Index-0.13

Instability Index33.99

Aliphatic Index 79.46

Aromaticity 0.0543

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4458.57

LogP -49.84

H-bond Donors 161.0

H-bond Acceptors 147.0

Rotatable Bonds 352.0

Heavy Atoms 719.0

Ring Count 9.0

Amide Bonds 99.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0287626 VERIFIED: NO

Provenance & Taxonomy

OrganismMus spicilegus [Animal]

FamilyDefensin

Tax ID10103

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal