Peptide Database

Peptide NameRuminococcin-A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC228H360N62O74S6

DescriptionStandard

        MRNDVLTLTNPMEENELEQILGGGNGVLKTISHECNMNTWQFLFTCC
    

Molecular Weight5346.06 Da

Isoelectric Point (pI)4.41

Net Charge (pH 7.0)-4.43

Net Charge (pH 7.4) -4.75

Charge Density (pH 7.0) -0.0942

GRAVY Index-0.21

Hydrophobic Moment 0.49

Boman Index0.07

Instability Index21.71

Aliphatic Index 78.72

Aromaticity 0.0638

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2215.42

LogP -23.49

H-bond Donors 76.0

H-bond Acceptors 77.0

Rotatable Bonds 179.0

Heavy Atoms 370.0

Ring Count 6.0

Amide Bonds 54.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0023979 VERIFIED: YES

Provenance & Taxonomy

OrganismBlautia hansenii [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetB. longum

RECORD: Rec_0409033 VERIFIED: NO

Provenance & Taxonomy

OrganismTyzzerella nexilis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Non-hemolytic Non-ribosomal