Peptide Database

Peptide NameSLAY-screened peptide P3856

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC48H73N15O18S

DescriptionStandard

        VSCDHNKYNT
    

Molecular Weight1180.25 Da

Isoelectric Point (pI)6.70

Net Charge (pH 7.0)-0.19

Net Charge (pH 7.4) -0.47

Charge Density (pH 7.0) -0.0190

GRAVY Index-1.37

Hydrophobic Moment 0.16

Boman Index-0.30

Instability Index99.73

Aliphatic Index 29.00

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 564.09

LogP -8.01

H-bond Donors 20.0

H-bond Acceptors 20.0

Rotatable Bonds 37.0

Heavy Atoms 82.0

Ring Count 2.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0317246 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/