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MYP_053650
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
3 amino acids
C20H31N3O5
Standard
Sequence
LVY
Physicochemical Analysis
393.48 Da
5.52
-0.24
-0.45
-0.0803
2.23
0.39
0.80
-18.47
226.67
0.3333
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
141.75
1.02
5.0
5.0
10.0
28.0
1.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0238753 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
1.8 μM
IC50
PaperNovel probiotic-fermented milk with angiotensin I-converting enzyme inhibitory peptides produced by Bifidobacterium bifidum MF 20/5. PMID24135669 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24135669/
RECORD: Rec_0309912 VERIFIED: NO
Provenance & Taxonomy
Sesamum indicum [Plant]
ACE-inhibitory peptide
4182
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive Antioxidant
Spontaneously hypertensive rat (SHR)
25 mmHg
SBP decrease
PaperVegetable foods: A cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities. PMID23598136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598136/
RECORD: Rec_0320912 VERIFIED: NO
Provenance & Taxonomy
Sesamum indicum [Plant]
ACE-inhibitory peptide
4182
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
0.33-5.8 μg/mL
IC50
PaperISOLATION AND CHARACTERIZATION OF PEPTIDES WITH ANTIHYPERTENSIVE ACTIVITY IN FOODSTUFFS. PMID24915368 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
RECORD: Rec_0351339 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
5.74 pIC50
pIC50
PaperWhat are the ideal properties for functional food peptides with antihypertensive effect? A computational peptidology approach. PMID23871047 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23871047/
RECORD: Rec_0364171 VERIFIED: YES
Provenance & Taxonomy
Sesamum indicum [Plant]
ACE inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory Antihypertensive
Angiotensin-converting enzyme
PaperIsolation and characterization of peptides with antihypertensive activity in foodstuffs | PubMed PMID 16717411 PMID16717411;24915360 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16717411/
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