Peptide Database

Peptide NameJindongenin-1a (Jindongenin-1)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC326H545N81O100S6

DescriptionStandard

        MFTLKKPLLLLFFLGTVSLSLCEQERAADDDEGEVIEEEVKRDSMGAVKLAKLLIDKMKCEVTKAC
    

Molecular Weight7391.69 Da

Isoelectric Point (pI)4.85

Net Charge (pH 7.0)-3.51

Net Charge (pH 7.4) -3.80

Charge Density (pH 7.0) -0.0532

GRAVY Index0.09

Hydrophobic Moment 0.57

Boman Index0.03

Instability Index38.23

Aliphatic Index 106.36

Aromaticity 0.0455

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2927.36

LogP -21.70

H-bond Donors 103.0

H-bond Acceptors 103.0

Rotatable Bonds 262.0

Heavy Atoms 513.0

Ring Count 4.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0400112 VERIFIED: YES

Provenance & Taxonomy

OrganismAmolops jingdongensis [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antioxidant Antifungal Anti-Candida Cytolytic Cytotoxic Hemolytic

TargetCandida albicans