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MYP_053634
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Basic Information
Microplusin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
90 amino acids
C429H671N131O143S8
Standard
Sequence
HHQELCTKGDDALVTELECIRLRISPETNAAFDNAVQQLNCLNRACAYRKMCATNNLEQAMSVYFTNEQIKEIHDAATACDPEAHHEHDH
Physicochemical Analysis
10208.23 Da
5.16
-7.66
-8.33
-0.0851
-0.62
0.53
-0.11
54.75
70.67
0.0444
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
4440.94
-51.07
154.0
150.0
340.0
711.0
13.0
101.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0003820 VERIFIED: YES
Provenance & Taxonomy
Rhipicephalus microplus [Animal]
Microplusin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperDev Comp Immunol. 2004 Mar;28(3):191-200. | http://www.ncbi.nlm.nih.gov/pubmed/14642886 PMID14642886 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14642886/
RECORD: Rec_0003929 VERIFIED: YES
Provenance & Taxonomy
Rhipicephalus microplus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Micrococcus luteus
0.38-0.76 μM
MIC
PMID14642886 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14642886/
RECORD: Rec_0047204 VERIFIED: YES
Provenance & Taxonomy
Boophilus microplus [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
6-52, 19-80, 41-46
Bio-Activity Profile
Antimicrobial Antifungal Antibacterial
Cryptococcus neoformans
PMID14642886;19828445 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14642886/
RECORD: Rec_0180919 VERIFIED: NO
Provenance & Taxonomy
Arthropoda [Animal]
6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0189674 VERIFIED: YES
Provenance & Taxonomy
Rhipicephalus microplus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
6-52; 19-80; 41-46
Bio-Activity Profile
Antimicrobial Antifungal Host defense
PaperPDB 2KNJ structural record; NMR; chain A; residues 1-90
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