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MYP_053606
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Basic Information
Latarcin-5
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
28 amino acids
C164H253N45O34S
Standard
Sequence
GFFGKMKEYFKKFGASFKRRFANLKKRL
Physicochemical Analysis
3431.11 Da
11.24
8.75
8.54
0.3127
-0.76
0.68
-0.25
45.20
35.00
0.2500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1337.71
-7.90
49.0
44.0
122.0
244.0
7.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0367611 VERIFIED: YES
Provenance & Taxonomy
Ant spider [Animal]; Animalia [Animal]
33208; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID16735513 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16735513/
RECORD: Rec_0381617 VERIFIED: YES
Provenance & Taxonomy
Lachesana tarabaevi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli DH5-alpha
0.6 μM
MIC
PMID16735513 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16735513/
RECORD: Rec_0404852 VERIFIED: YES
Provenance & Taxonomy
Lachesana tarabaevi [Animal]
Latarcin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PAO1
18 μM
MIC
PMID16735513;19563807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16735513/
RECORD: Rec_0419623 VERIFIED: YES
Provenance & Taxonomy
Lachesana tarabaevi [Animal]
Latarcin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa
18 μM
MIC
PaperLatarcins, antimicrobial and cytolytic peptides from the venom of the spider Lachesana tarabaevi (Zodariidae) that exemplify biomolecular diversity. PMID16735513 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16735513/
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