Peptide Database

Peptide Nameantisauvagine

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC161H273N47O47S

DescriptionStandard

        FHLLRKMIEIEKQEKEKQQAANNRLLLDTI
    

Molecular Weight3651.24 Da

Isoelectric Point (pI)8.44

Net Charge (pH 7.0)0.86

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0285

GRAVY Index-0.76

Hydrophobic Moment 0.62

Boman Index-0.23

Instability Index86.26

Aliphatic Index 110.67

Aromaticity 0.0333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1585.96

LogP -12.27

H-bond Donors 53.0

H-bond Acceptors 50.0

Rotatable Bonds 134.0

Heavy Atoms 256.0

Ring Count 2.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0062591 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor antagonist Signaling peptide

TargetCRF2 receptor (Human)

Activity0.25-1.58 nM

MethodKd