Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length186 amino acids

Chemical FormulaC913H1449N247O244S8

DescriptionStandard

        PTALPMAHEPMLLVAVTELVANSAAFAYFTAGALRRSISSHMLPRHFPLQLRTKSLGVFAPQLQEHYPDQPMELQLSARRQPLLSCHPNGLHGTLFGSAEAFVVLPNATRVPAFLLNIDANVTGKPTVTGKRLGGTVKLTGCVSSPVLGLGLPVLQVKNLENLLKFGLWLFGVPWANSECCPHPVI
    

Molecular Weight20046.30 Da

Isoelectric Point (pI)9.32

Net Charge (pH 7.0)5.54

Net Charge (pH 7.4) 5.05

Charge Density (pH 7.0) 0.0298

GRAVY Index0.25

Hydrophobic Moment 0.60

Boman Index0.19

Instability Index57.49

Aliphatic Index 103.28

Aromaticity 0.0699

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7634.63

LogP -86.38

H-bond Donors 261.0

H-bond Acceptors 264.0

Rotatable Bonds 632.0

Heavy Atoms 1412.0

Ring Count 40.0

Amide Bonds 200.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0072855 VERIFIED: NO

Provenance & Taxonomy

OrganismBaryphthengus martii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria