Peptide Database

Peptide NameSLAY-screened peptide P3079

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC52H82N18O16

DescriptionStandard

        IIHHVTTGHNS
    

Molecular Weight1215.32 Da

Isoelectric Point (pI)7.02

Net Charge (pH 7.0)0.02

Net Charge (pH 7.4) -0.33

Charge Density (pH 7.0) 0.0020

GRAVY Index-0.23

Hydrophobic Moment 0.36

Boman Index0.19

Instability Index26.40

Aliphatic Index 97.27

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 544.14

LogP -6.85

H-bond Donors 19.0

H-bond Acceptors 19.0

Rotatable Bonds 37.0

Heavy Atoms 86.0

Ring Count 3.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0348100 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/