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MYP_053540
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Basic Information
Ranatuerin-2ARa (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
28 amino acids
C123H217N35O39S4
Standard
Sequence
GLMDTVKNAAKNLAGQLLDTIKCKMTGC
Physicochemical Analysis
2938.51 Da
8.82
1.74
1.50
0.0621
0.06
0.62
0.05
2.43
90.71
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1217.66
-13.68
43.0
45.0
104.0
201.0
0.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002514 VERIFIED: YES
Provenance & Taxonomy
Rana areolata [Animal]
Ranatuerin
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
23-28
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic
human erythrocytes
100 μM
HC50
PaperPubMed PMID: 12429503 PMID12429503 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12429503/
RECORD: Rec_0018959 VERIFIED: YES
Provenance & Taxonomy
Rana areolata [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
23-28
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic
human erythrocytes
100 μM
HC50
RECORD: Rec_0044491 VERIFIED: YES
Provenance & Taxonomy
Rana areolata [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
100
HC50
PMID12429503 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12429503/
RECORD: Rec_0052460 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Toxic Hemolytic
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0055939 VERIFIED: YES
Provenance & Taxonomy
Rana areolata [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
23-28
Bio-Activity Profile
Antimicrobial
Escherichia coli
30 μM
MIC
PaperAntimicrobial peptides and protease inhibitors in the skin secretions of the crawfish frog, Rana areolata.
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