Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length113 amino acids

Chemical FormulaC539H867N145O160S3

DescriptionStandard

        DLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRGAVHISKVFVTAILSTPLDNAGPTSIALTSCWTTPGDVDIKLNGKT
    

Molecular Weight12034.72 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)2.02

Net Charge (pH 7.4) 1.63

Charge Density (pH 7.0) 0.0178

GRAVY Index0.15

Hydrophobic Moment 0.60

Boman Index0.17

Instability Index22.72

Aliphatic Index 102.65

Aromaticity 0.0619

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4845.14

LogP -50.74

H-bond Donors 170.0

H-bond Acceptors 168.0

Rotatable Bonds 393.0

Heavy Atoms 847.0

Ring Count 18.0

Amide Bonds 119.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0089193 VERIFIED: NO

Provenance & Taxonomy

OrganismQuiscalus mexicanus (Great-tailed grackle) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria