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MYP_053493
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Basic Information
[Arg]11-VmCT1-NH2 (Derived from VmCT1)
Anticancer
Anticancer ▸ Antitumor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C75H113N19O15
Standard
Sequence
FLGALWNVAKRVF
Physicochemical Analysis
1520.82 Da
11.00
1.76
1.55
0.1353
0.92
0.58
0.34
55.48
120.00
0.2308
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
559.32
-1.23
20.0
17.0
47.0
109.0
4.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0073057 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli SBS 363 (MIC=1.6 μmol/L)，Serratia marcescens ATCC 4112
0.2 μM
MIC
PaperRepurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0112045 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Bacillus megaterium ATCC 10778
0.8 μM
MIC
PaperRepurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0125327 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus ATCC 29213
1.6 μM
MIC
PaperRepurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
RECORD: Rec_0139240 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Human RBCs [Hemolysis observed in the range 0.1 –100 micromol/L
100
Hemolysis
PMID33442883;31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33442883/
RECORD: Rec_0157796 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans MDM8
0.8 μM
MIC
PaperRepurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens PMID31212183 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31212183/
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