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MYP_053481
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Basic Information
MPG
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
27 amino acids
C129H208N36O32S
Standard
Sequence
GALFLGFLGAAGSTMGAWSQPKKKRKV
Physicochemical Analysis
2807.32 Da
11.33
4.76
4.55
0.1762
-0.00
0.21
0.12
23.39
68.89
0.1111
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1096.68
-10.09
39.0
38.0
94.0
198.0
5.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0125821 VERIFIED: YES
Provenance & Taxonomy
porcine cathelicidin peptide [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PBMC
65 μM
IC50
PaperSelective anticancer activity of synthetic peptides derived from the host defence peptide tritrpticin. Biochim Biophys Acta Biomembr. 2020 Aug 1;1862(8):183228. doi: 10.1016/j.bbamem.2020.183228. PMID: 32126228. PMID32126228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32126228/
RECORD: Rec_0137585 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
MPG
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID24275947 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24275947/
RECORD: Rec_0190986 VERIFIED: YES
Provenance & Taxonomy
porcine cathelicidin peptide [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
RBC
65 μM
IC50
PaperSelective anticancer activity of synthetic peptides derived from the host defence peptide tritrpticin. Biochim Biophys Acta Biomembr. 2020 Aug 1;1862(8):183228. doi: 10.1016/j.bbamem.2020.183228. PMID: 32126228. PMID32126228 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32126228/
RECORD: Rec_0199493 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
MPG
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Cell-penetrating peptide
PMID12771197 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12771197/
RECORD: Rec_0254294 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Biotinylation
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PaperNew transport peptides broaden the horizon of applications for peptidic pharmaceuticals PMID15209161 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15209161/
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