Peptide Database

Peptide NameColicin D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length484 amino acids

Chemical FormulaC2212H3595N653O709S11

DescriptionStandard

        MDEYDYNNGVPPVTGNVWLPADEDGPGRWVAPTSGSWNGDTLTVTPSGGSSAGQDGMAYGGGSYGKTPSRLQAESSAAIHATAKWTTENLKKTQAAQAERVRATMAARQAARASQDKLRQKLTDVTNAAIQKGREGPSVTDVAHQTIKEMEAFAQMVAQNEARKKGRERGQKAEEAYQAALRAEEEARRQQAEIERKLKEAREREAAAKAKALADKAGAEKAEADRRALFTKAGIQDTPVYTTEMVKAANATLSAGSSLMLSRAPGMIQLSASGVGTLPFNSGLAGWEASALWRGVDVLARIAPVASTVVTVATVLTLIRSALDIPAVGEGSDRVPGRNIDMLATQASLYTAMKTKIQPGMKTVDLPVRGYISDDGNGRQSVNLVRTGTGGISATVPVLNTVRDKTTGLDKITVPAVAGAPSRTILVNPFPVGPNVPAHTGNEGTVPVTPVHTGTEVKQADSIVTTTLPTADIPALQDFIYWQP
    

Molecular Weight51033.87 Da

Isoelectric Point (pI)8.98

Net Charge (pH 7.0)3.92

Net Charge (pH 7.4) 3.39

Charge Density (pH 7.0) 0.0081

GRAVY Index-0.36

Hydrophobic Moment 0.77

Boman Index-0.02

Instability Index34.64

Aliphatic Index 76.71

Aromaticity 0.0434

Extinction Coeff. Reduced 51910.00

Extinction Coeff. Oxidized 51910.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0217746 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella oxytoca [Bacterium]

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli