Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length445 amino acids

Chemical FormulaC2202H3576N610O612S14

DescriptionStandard

        QKGLDYACQQGVAVLQKELEKIRIPDVSGKFKLRPFGKGHYNFHSLVVRSFQLPNPQIRLQPNVGLRVSISNANVRIGGRWKARKGFIKVRGKFDLSVEGVSISADLKLGSVPASGRATVTCSSCSSNINRARLRSQASWGGWLKLFHKRIESSLRNTMNSKICQVLTSSVSSKLQPYVETLPLKERLDSVAGIDYSLVAPPRATADSLDMQLKGEFYNVARPSPPPFMPPPMAIPSLHDRMIYLAISDYLFNTAALVYQQAGAFGLTLRDDMIPKESKSRLTTKFLGKALPQVAKMFPNMNVQLTLSVSSPPHLTTRPTGIALTAAVDLQAFAILPNSSLASLFLLGLKLNTSAKIGTKADKLVGELTLGRLILELKHSNIGSFPVQLLQALMDYVLSAVVLPKVNEKLQRGLPLPMPRKVQLYDLVLQPHQDFLLLGANVQHG
    

Molecular Weight48836.58 Da

Isoelectric Point (pI)10.09

Net Charge (pH 7.0)27.43

Net Charge (pH 7.4) 26.67

Charge Density (pH 7.0) 0.0616

GRAVY Index-0.02

Hydrophobic Moment 0.67

Boman Index0.06

Instability Index44.04

Aliphatic Index 102.54

Aromaticity 0.0674

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 31650.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0199729 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

Tax ID9986

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

RECORD: Rec_0268847 VERIFIED: NO