Peptide Database

Peptide NameDermaseptin-PS2

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC377H616N100O123S3

DescriptionStandard

        MAFLKKSLFLVLFLGLVSLSICEEEKRENEDEEKQEDDEQSEEKRALWKTLLKNVGKAAGKAVLNAVTDMVNQGEQ
    

Molecular Weight8613.72 Da

Isoelectric Point (pI)4.71

Net Charge (pH 7.0)-5.48

Net Charge (pH 7.4) -5.75

Charge Density (pH 7.0) -0.0721

GRAVY Index-0.50

Hydrophobic Moment 0.65

Boman Index-0.10

Instability Index55.76

Aliphatic Index 92.37

Aromaticity 0.0526

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3682.49

LogP -33.96

H-bond Donors 124.0

H-bond Acceptors 121.0

Rotatable Bonds 310.0

Heavy Atoms 603.0

Ring Count 5.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0404099 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllomedusa sauvagei [Bacterium]

FamilyFrog skin active peptide (FSAP) family; Dermaseptin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Amphibian defense peptide Non-hemolytic Non-ribosomal