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MYP_053385
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
36 amino acids
C167H262N48O50S6
Standard
Sequence
DHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK
Physicochemical Analysis
3934.55 Da
8.87
3.78
3.43
0.1051
-0.27
0.49
-0.03
34.49
46.11
0.1111
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1596.10
-19.74
62.0
61.0
128.0
271.0
6.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0096388 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
beta-defensin family
9606; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
5-34; 12-27; 17-35
Bio-Activity Profile
Antimicrobial beta-defensin family Antibacterial Host defense Defensin-like
PaperPDB 2NLD structural record; X-ray; 1.49 A; chain A/B; residues 1-36
RECORD: Rec_0098137 VERIFIED: NO
Provenance & Taxonomy
Animalia [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
RECORD: Rec_0111693 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiofilm Antifungal
Cryptococcus neoformans B3501
2, 4, 8 μM
XTT assay; Total countable CFUs
RECORD: Rec_0142580 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antitrypanosomal
Trypanosoma brucei brucei 427
>50 μM
Percent inhibition; MTT assay
PaperKilling of African trypanosomes by antimicrobial peptides PMID12825184 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12825184/
RECORD: Rec_0188641 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US7384911B2/en PatentUS 7384911 B2
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