Peptide Database

Peptide NameCART(1-52)

Function Ontology

Cardiovascular

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length52 amino acids

Chemical FormulaC256H427N75O82

DescriptionStandard

        QEDAELQPRALDIYSAVDDASHEKELPRRQLRAPGAVLQIEALQEVLKKLKS
    

Molecular Weight5867.58 Da

Isoelectric Point (pI)5.22

Net Charge (pH 7.0)-2.14

Net Charge (pH 7.4) -2.41

Charge Density (pH 7.0) -0.0411

GRAVY Index-0.65

Hydrophobic Moment 0.68

Boman Index-0.18

Instability Index65.39

Aliphatic Index 105.19

Aromaticity 0.0192

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2570.78

LogP -24.28

H-bond Donors 86.0

H-bond Acceptors 81.0

Rotatable Bonds 203.0

Heavy Atoms 413.0

Ring Count 5.0

Amide Bonds 56.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0125018 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyCART

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

RECORD: Rec_0225998 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyCART(1-52)

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other Mods14:Phosphotyrosine; 21:Phosphoserine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory Feeding regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour