Peptide Database

Peptide NameCecropin A (1-8) + Magainin 2 (1-6)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC87H140N20O15

DescriptionStandard

        KWKLFKKIGIGKFL
    

Molecular Weight1706.17 Da

Isoelectric Point (pI)10.60

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.3397

GRAVY Index0.07

Hydrophobic Moment 0.30

Boman Index0.11

Instability Index-25.71

Aliphatic Index 111.43

Aromaticity 0.2143

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 587.51

LogP 1.00

H-bond Donors 21.0

H-bond Acceptors 20.0

Rotatable Bonds 61.0

Heavy Atoms 122.0

Ring Count 4.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0348275 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMagainin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetStaphylococcus epidermidis KCTC 3096

Activity6.25 μM

MethodMIC

RECORD: Rec_0417811 VERIFIED: YES