Peptide Database

Peptide NameBombinin-like peptide 4 (BLP-4; toads, amphibians, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC109H182N30O31

DescriptionStandard

        GIGAAILSAGKSIIKGLANGLAEHF
    

Molecular Weight2408.79 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0339

GRAVY Index0.78

Hydrophobic Moment 0.61

Boman Index0.40

Instability Index-12.85

Aliphatic Index 129.20

Aromaticity 0.0400

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 963.29

LogP -9.20

H-bond Donors 33.0

H-bond Acceptors 33.0

Rotatable Bonds 82.0

Heavy Atoms 170.0

Ring Count 2.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416735 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina orientalis [Animal]

FamilyBombinin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetNeisseria gonorrhoeoe

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