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MYP_053315
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Basic Information
Ligand of neurotensin receptor
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Lipase inhibition
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Sensory / Food function ▸ Taste-active peptide
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-aging
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Anti-wrinkle
Therapeutic / Biomedical activity ▸ Dermatology / Cosmetic bioactivity ▸ Skin aging modulation ▸ Collagen boosting
Standard
2 amino acids
C14H18N2O4
Standard
Sequence
PY
Physicochemical Analysis
278.30 Da
5.95
-0.04
-0.10
-0.0213
-1.45
0.13
0.19
5.00
0.00
0.5000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
98.66
0.26
4.0
4.0
5.0
20.0
2.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007236 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Neurotensin
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
PaperCain G. A., Christos T. E., Johnson A. L., Pottorf R. S., Tam S., Schmidt W. K.. Identification of simpler analogs of neurotensin(913) which retain antinociceptive activity. Bioorg. Med. Chem. Lett., 3, 1767-1772, 1993.
RECORD: Rec_0029986 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Dipeptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-aging Anti-wrinkle Collagen boosting
Mouse melanoma (B16 cells) (In vitro)
Immunostaining; Melanin assay
PaperPatent US 10660839 B2 PatentUS 10660839 B2
RECORD: Rec_0135355 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Dipeptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-aging Anti-wrinkle Collagen boosting
Human keratinocytes (In vitro)
Immunostaining; Melanin assay
PaperPatent US 10660839 B2 PatentUS 10660839 B2
RECORD: Rec_0198957 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Model sensory peptide
32630
Structure & Mods
linear contiguous peptide sequence [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Bitter
PaperQuantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives. J. Med. Chem., 30, 1873-1879, 1987
RECORD: Rec_0203283 VERIFIED: NO
Provenance & Taxonomy
Juglans regia [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-inflammatory Enzyme inhibitory Taste
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