Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC365H570N94O106S11

DescriptionStandard

        MRIFYYLHFLCYVTFILPTTCTLVDADCCTKRYGRCKRDCLEIEKQIDICSSPRKICCTERLYEEDDMF
    

Molecular Weight8323.71 Da

Isoelectric Point (pI)5.71

Net Charge (pH 7.0)-1.49

Net Charge (pH 7.4) -1.91

Charge Density (pH 7.0) -0.0216

GRAVY Index-0.09

Hydrophobic Moment 0.60

Boman Index-0.06

Instability Index69.23

Aliphatic Index 77.68

Aromaticity 0.1304

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3245.08

LogP -24.75

H-bond Donors 125.0

H-bond Acceptors 117.0

Rotatable Bonds 274.0

Heavy Atoms 576.0

Ring Count 12.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418118 VERIFIED: NO

Provenance & Taxonomy

OrganismPan paniscus [Animal]

FamilyDefensin

Tax ID9597

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence