Peptide Database

Peptide NameBeta-defensin 10

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC348H550N98O100S10

DescriptionStandard

        MKTLCSLLLIGCLLFSYDTPVVGELKHLGMTAETEWCRLFEGFCHDKNCPPPTSHVGSCHPEKRSCCKDRR
    

Molecular Weight8027.34 Da

Isoelectric Point (pI)7.58

Net Charge (pH 7.0)0.78

Net Charge (pH 7.4) 0.23

Charge Density (pH 7.0) 0.0110

GRAVY Index-0.23

Hydrophobic Moment 0.60

Boman Index-0.02

Instability Index56.77

Aliphatic Index 68.59

Aromaticity 0.0704

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3128.60

LogP -30.13

H-bond Donors 117.0

H-bond Acceptors 115.0

Rotatable Bonds 260.0

Heavy Atoms 556.0

Ring Count 15.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0227683 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q32ZI1/entry; https://bblserver.org.in/ampdb/