Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length135 amino acids

Chemical FormulaC676H1077N189O180S5

DescriptionStandard

        QLQERYPDQPMELHLWARQQPLLSCHPDALHGTLFGSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPQLAWTPLPVLCQAQGLPVPQVKRLETLLKFGLWLFGVPRANSKCCPRSVP
    

Molecular Weight14892.27 Da

Isoelectric Point (pI)9.43

Net Charge (pH 7.0)4.99

Net Charge (pH 7.4) 4.56

Charge Density (pH 7.0) 0.0370

GRAVY Index-0.02

Hydrophobic Moment 0.54

Boman Index0.09

Instability Index46.96

Aliphatic Index 100.37

Aromaticity 0.0667

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 18240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5801.55

LogP -50.23

H-bond Donors 197.0

H-bond Acceptors 193.0

Rotatable Bonds 465.0

Heavy Atoms 1050.0

Ring Count 31.0

Amide Bonds 148.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0016785 VERIFIED: NO

Provenance & Taxonomy

OrganismPromerops cafer [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria