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MYP_053149
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Basic Information
Laxaphycin A
Anticancer
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
12 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XXEXXXFLIILG
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017734 VERIFIED: NO
Provenance & Taxonomy
Anabaena laxa [Bacterium]
Structure & Mods
topology not specified [Not included yet]
noncanonical/placeholder residue-containing peptide [Modified]
None
None
Contains X placeholder residue(s)
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID15875779 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15875779/
RECORD: Rec_0162164 VERIFIED: NO
Provenance & Taxonomy
Anabaena laxa [Bacterium]
Structure & Mods
topology not specified [Not included yet]
noncanonical/placeholder residue-containing peptide [Modified]
None
None
Contains X placeholder residue(s)
Bio-Activity Profile
Antimicrobial Anticancer
PMID15875779 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15875779/
RECORD: Rec_0186718 VERIFIED: YES
Provenance & Taxonomy
Anabaena laxa [Bacterium]
Terrestrial blue-green alga Anabaena laxa or the marine cyanobacterium Lyngbya Majuscula
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Aoc = 3-aminooctanoic acid ,Hyp = 4- hydroxyproline, Dhb = didehydrobutyrine, Hse = Homoserine
Bio-Activity Profile
Antifungal
CEM-VLB
4 μM
Inhibition
PMID15875779;1429232 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15875779/
RECORD: Rec_0188979 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
residue-level stereochemical modification [Mixed]
None
None
Aoc = 3-aminooctanoic acid ,Hyp = 4- hydroxyproline, Dhb = didehydrobutyrine, Hse = Homoserine
Bio-Activity Profile
Anticancer Antimicrobial Antifungal
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0247210 VERIFIED: YES
Provenance & Taxonomy
Anabaena laxa [Bacterium]
Terrestrial blue-green alga Anabaena laxa or the marine cyanobacterium Lyngbya Majuscula
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Aoc = 3-aminooctanoic acid ,Hyp = 4- hydroxyproline, Dhb = didehydrobutyrine, Hse = Homoserine
Bio-Activity Profile
Antifungal
CEM-WT
4 μM
Inhibition
PMID15875779;1429232 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15875779/
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