Peptide Database

Peptide NameAlpha-defensin 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC446H717N137O147S7

DescriptionStandard

        MKTLVLLSALVLLAFQVQADPIQNTDEETNTEEQAGEEDQAVSVSFGDPEGSALHEKSSRDLICYCRKGGCNRGEQVYGTCSGRLLFCCRRRHRH
    

Molecular Weight10574.75 Da

Isoelectric Point (pI)5.54

Net Charge (pH 7.0)-3.27

Net Charge (pH 7.4) -3.75

Charge Density (pH 7.0) -0.0344

GRAVY Index-0.50

Hydrophobic Moment 0.62

Boman Index-0.13

Instability Index39.79

Aliphatic Index 73.89

Aromaticity 0.0526

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4633.67

LogP -55.79

H-bond Donors 167.0

H-bond Acceptors 154.0

Rotatable Bonds 359.0

Heavy Atoms 737.0

Ring Count 10.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0396678 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence