Peptide Database

Peptide NamePyocin-S2 (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length1202 amino acids

Chemical FormulaC5889H9159N1649O1847S31

DescriptionStandard

        MDNWLALFDGQTRYSLEINDSTVLPDVLNFTGREALSEPFSWDIEFTTPQANIAPEQVLMKYGSLRMRSGKSVHGIITRLEWLSTTQDQSHYKVTLSSRLALLSFTRQCAVFQNQSVPEVVEQVLRQHGLEGPDFEFRLERTYPARELITQWRETDLEFVQRILSEVGIYWRTEMDSTREMDVYLFADSQLNYQFDVRLPYSEPSGLYDGAAESVWDVRTRNNVVTGTVATRDYNYRAASTPLDTAVSVRQDASMTGEQYRYAAPYREAGDDTEPEPETESGAFYARIHHERELNKSARVSLDSNASGLTPGQVLEPQGNVIAALSEGVIITLVTYRAARDTRLHVSVEGMPYSERYSFRPVEIPRPEIHGTLPARIESREKNDTYAYLDEQGRYRVKLDFDREGSEQGYGYLWLRMAKPYSGDTLGWHTPLIDGTEVAIAYGNGDIDLPYISHAMHDSEHPDHVNRDNHTRNVLRTPANNKLRMEDQRGEEHIKLATEYGKTQLNTGHLVDEKAQPRGKGTELRTDERGTIRAGKGLYVSADGQAKAQGEVLDMDAALKEIDQLNQQLQQLEMAAEQALALKADIDSQIQMFEQRLKPLNEALLFSAPEGIAFTSGEHLQLTATKNLAINAGGDISAGVMGNMTALAGEKLGLFARTGQLSLKAGEGPIDMQAQNASMRLFAEKKLTFTSESDISFAGKKRITLIGGGSYLKLEAGKVEYGTTASYIRKVKRTMFAAPNALPLETVSLPPPATMREFNPETLTPWVTPVYAKSCLKEKGCTDGGTNEESADNFGEMTIFAQPVEDDCCGYGHQHEHDDEVVQHAQSAKRRKPGSESAVAPAEASAAPLAIGGGALAARTTAGVMTQVWGEWSLTGVLGAARGIPYVGAMMSALYIPSAGAGSDKVPGRDEYWYEEELRQKALTGAKATTRVRFFWHADDQGNMRVYGVHTGEGTPYEGVRTADMKWVEANNRYEFTPAHGVDGPLITWTPEKPEGSDLPSHTGSDIKPIDQATILVTPIPDGKDEYTTPPFPVPEERDLNDYILVFPADSGIKPIYVYLKDDSRSQPGTATGNGAQIENGKNWLDLSVTNSGEGAKIPAHIADKLRRKKYNTFNELREDIWMEISNDPDLLAQFGEDNQERISGGLAPWVPKDGYYIGPKEVVKKFQIHHDIAIENGGGVYDIDNLRIVTPRLHDEIHYRR
    

Molecular Weight133604.68 Da

Isoelectric Point (pI)5.13

Net Charge (pH 7.0)-45.76

Net Charge (pH 7.4) -47.88

Charge Density (pH 7.0) -0.0381

GRAVY Index-0.54

Hydrophobic Moment 0.72

Boman Index-0.04

Instability Index31.79

Aliphatic Index 75.27

Aromaticity 0.0832

Extinction Coeff. Reduced 172010.00

Extinction Coeff. Oxidized 172260.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0210654 VERIFIED: NO

Provenance & Taxonomy

OrganismButtiauxella agrestis [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence