Peptide Database

Peptide NameBrevinin 1Pf

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC223H361N59O68S2

DescriptionStandard

        NAEEERRDEPDETDVEVEKRFLPIIAGIAAKFLPKIFCAISKKC
    

Molecular Weight5020.74 Da

Isoelectric Point (pI)4.96

Net Charge (pH 7.0)-2.24

Net Charge (pH 7.4) -2.50

Charge Density (pH 7.0) -0.0509

GRAVY Index-0.39

Hydrophobic Moment 0.60

Boman Index-0.11

Instability Index52.58

Aliphatic Index 86.59

Aromaticity 0.0682

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2060.60

LogP -16.12

H-bond Donors 71.0

H-bond Acceptors 68.0

Rotatable Bonds 171.0

Heavy Atoms 352.0

Ring Count 6.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0096145 VERIFIED: NO

Provenance & Taxonomy

OrganismLithobates pipiens [Animal]

FamilyBrevinin

Tax ID8404

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0329816 VERIFIED: NO