Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length165 amino acids

Chemical FormulaC810H1308N230O243S8

DescriptionStandard

        MNNQLKKRLLVATAGGVLALAAVLVQWHEGKRYKPYRDGGGVLTVCHGHTGKDVTPEEIYSEEECSELMRRDLQIARSVVEHYVTFPLSDLQKAALTSFVYNIGSGAFERSTLLKKLNVGDLSGACDEMCRWKYDEGKVSKGLINRRAIERELCLKPDLLTSPTQ
    

Molecular Weight18412.97 Da

Isoelectric Point (pI)8.25

Net Charge (pH 7.0)1.83

Net Charge (pH 7.4) 1.28

Charge Density (pH 7.0) 0.0111

GRAVY Index-0.31

Hydrophobic Moment 0.67

Boman Index-0.04

Instability Index57.44

Aliphatic Index 90.97

Aromaticity 0.0667

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 20190.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7651.16

LogP -74.73

H-bond Donors 273.0

H-bond Acceptors 257.0

Rotatable Bonds 624.0

Heavy Atoms 1291.0

Ring Count 22.0

Amide Bonds 174.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0279293 VERIFIED: NO

Provenance & Taxonomy

OrganismCandidatus Hamiltonella defensa [Fungus]

FamilyLysozyme

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence