Peptide Database

Peptide NameColicin E3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length181 amino acids

Chemical FormulaC890H1380N250O273S2

DescriptionStandard

        MGQHRQAYTFTTEEESPVTIIWTPDHSGANTPTNTGNQTPPRLPGTILVNPLPDGTQITSTTTPAPDEKNFADYILILPVSDIPPIYIYLNADHKYHVAPRGTPPLPAFPDAKTAKKRTPVKGGGTLRSSWKDSKGRIFEWDSQHGTVEMYDRSGRNHLGEFDPVSGEQTKPADPTRRVKK
    

Molecular Weight20014.12 Da

Isoelectric Point (pI)7.97

Net Charge (pH 7.0)1.04

Net Charge (pH 7.4) 0.48

Charge Density (pH 7.0) 0.0058

GRAVY Index-0.82

Hydrophobic Moment 0.61

Boman Index-0.09

Instability Index46.70

Aliphatic Index 59.28

Aromaticity 0.0773

Extinction Coeff. Reduced 25440.00

Extinction Coeff. Oxidized 25440.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8307.52

LogP -100.85

H-bond Donors 281.0

H-bond Acceptors 282.0

Rotatable Bonds 627.0

Heavy Atoms 1415.0

Ring Count 45.0

Amide Bonds 193.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0384485 VERIFIED: NO

Provenance & Taxonomy

OrganismLeclercia sp. 29361 [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative

TargetEscherichia coli