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MYP_053044
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Basic Information
Temporin-Sha[K3]
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C70H115N15O14S
Standard
Sequence
FLKGIVGMLGKLF
Physicochemical Analysis
1422.82 Da
10.00
1.76
1.55
0.1352
1.43
0.51
0.55
-36.48
142.31
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
464.56
0.45
16.0
17.0
49.0
100.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000587 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 30669255 PMID30669255 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30669255/
RECORD: Rec_0029524 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Listeria ivanovii
128 μM
MBC
PMID30813478 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30813478/
RECORD: Rec_0035257 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 30669255 PMID30669255 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30669255/
RECORD: Rec_0039203 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Listeria ivanovii
64 μM
MIC
PMID30813478 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30813478/
RECORD: Rec_0088102 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
HSV-1:inhibition of HSV-1 replication in human keratinocytes ,57% inhibition at 5 μM
48 %
Inhibition
PaperPubMed PMID: 30669255 PMID30669255 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30669255/
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