Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC372H598N106O98S9

DescriptionStandard

        MRIPVLLFTIFFFMSQVLPARGKFKEICERPNGSCRDFCLKTEIHVGRCLNSRPCCLPLGHQPRIESTTPKMD
    

Molecular Weight8411.96 Da

Isoelectric Point (pI)9.15

Net Charge (pH 7.0)4.63

Net Charge (pH 7.4) 4.21

Charge Density (pH 7.0) 0.0634

GRAVY Index-0.09

Hydrophobic Moment 0.47

Boman Index-0.02

Instability Index60.41

Aliphatic Index 77.40

Aromaticity 0.0822

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3249.73

LogP -28.32

H-bond Donors 118.0

H-bond Acceptors 114.0

Rotatable Bonds 274.0

Heavy Atoms 585.0

Ring Count 15.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0045854 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca nemestrina [Animal]

FamilyDefensin

Tax ID9545

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0076329 VERIFIED: NO