Peptide Database

Peptide Name[D-Phe6, Leu13, Cpa14,ψ13-14]bombesin-(6-14)

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC56H73N13O11

DescriptionStandard

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Molecular Weight1104.26 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0170

GRAVY Index0.82

Hydrophobic Moment 0.31

Boman Index0.58

Instability Index-17.24

Aliphatic Index 86.67

Aromaticity 0.3333

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 383.68

LogP 0.07

H-bond Donors 13.0

H-bond Acceptors 12.0

Rotatable Bonds 31.0

Heavy Atoms 80.0

Ring Count 5.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0110036 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Receptor antagonist Neuropeptide activity Signaling peptide

TargetBB1 receptor (Human); BB2 receptor (Human); BB2 receptor (Rat)

Activity>10000 nM

MethodIC50