Peptide Database

Peptide NameSLAY-screened peptide P3162

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC56H90N18O17

DescriptionStandard

        HDLYNVKKRD
    

Molecular Weight1287.42 Da

Isoelectric Point (pI)8.50

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0850

GRAVY Index-1.93

Hydrophobic Moment 0.34

Boman Index-0.61

Instability Index38.72

Aliphatic Index 68.00

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 605.76

LogP -5.28

H-bond Donors 21.0

H-bond Acceptors 19.0

Rotatable Bonds 44.0

Heavy Atoms 91.0

Ring Count 2.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0200398 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/