Peptide Database

Peptide NameBrevinin-1CDYa

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC353H580N90O103S4

DescriptionStandard

        MFTLKKSLLLIFFLGTINLSLCEEERNADEEERRDDLEERDVEVEKRLLSLALAALPKLFCLIFKKC
    

Molecular Weight7861.18 Da

Isoelectric Point (pI)4.93

Net Charge (pH 7.0)-3.50

Net Charge (pH 7.4) -3.79

Charge Density (pH 7.0) -0.0523

GRAVY Index0.03

Hydrophobic Moment 0.56

Boman Index-0.03

Instability Index47.87

Aliphatic Index 119.40

Aromaticity 0.0746

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3150.28

LogP -20.36

H-bond Donors 112.0

H-bond Acceptors 104.0

Rotatable Bonds 277.0

Heavy Atoms 550.0

Ring Count 6.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0209599 VERIFIED: YES

Provenance & Taxonomy

OrganismRana dybowskii [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0271509 VERIFIED: YES