Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length176 amino acids

Chemical FormulaC874H1399N241O237S5

DescriptionStandard

        PTAPPAADEPMLLVAVTELVANSAAFAYFTAGALRRNLSSDTLPRRFPLQLRTKSLGLIAPQLQELYPDQPMELQLWARRQPLLSCRPDALHGTLFGSAEAFVVLPNATRVPAFLLNIDANVTGKPTISGHRLGGRVKLTGMLVPQVKSLENLLKFGLWLFGVPWANSECRLRVSP
    

Molecular Weight19235.26 Da

Isoelectric Point (pI)9.91

Net Charge (pH 7.0)6.13

Net Charge (pH 7.4) 5.92

Charge Density (pH 7.0) 0.0348

GRAVY Index0.10

Hydrophobic Moment 0.60

Boman Index0.10

Instability Index55.99

Aliphatic Index 103.69

Aromaticity 0.0739

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7536.64

LogP -79.41

H-bond Donors 260.0

H-bond Acceptors 250.0

Rotatable Bonds 612.0

Heavy Atoms 1357.0

Ring Count 35.0

Amide Bonds 189.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0126739 VERIFIED: NO

Provenance & Taxonomy

OrganismTodus mexicanus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria